Mary Allan Wilson showed the genetic similarities between chimpanzees

Mary Claire King is a human geneticist. But long before that she was a whole another person. Now you might be asking who is mary claire king? Mary claire King was born on February 27, 1946, in Evanston, Il. She was born in Chicago. After she graduated she went to the university of california to be a doctorate in statistics. But later on she realized that it wasn’t for her and fell in love with the application of mathematics and statics to solving genetic problems. Then she went  to the genetics program in 1967, and for the first time started doing experimental biology. Most of the work she has done has changed the way people view life in general.         One of those things was discovering the region on the genome that eventually became known as BRCA1, the first gene linked to a bigger chance of getting breast cancer and ovarian cancer. But most people thought it was to crazy so the thought didn’t have many supporters. But later on it transformed the diagnosis and treatment of the disease.         Now onto a very exciting topic for me anyways in 1946 Mary Claire King and Allan Wilson showed  the genetic similarities between chimpanzees and humans. They showed us that chimpanzees and humans shared ninety-nine percent of their DNA. This thought was all ready in the air but, many scientists were still doubtful of the relationship between chimpanzees and humans. However, the scientist found evidence supported the theory that chimpanzees and humans have a genetic tie. Wow us related to monkeys.         Mary claire king had studied a large Costa Rican family with autosomal dominant progressive non-syndromic hearing loss and have recently through positional cloning identified a protein truncation mutation in the human homologue of the Drosophila diaphanous gene. This mutation was found in all deaf family members and not in normal hearing family members or over 300 control individuals. Treacher-Collins syndrome, characterized by deafness with other severe abnormalities, has also been mapped on the same part of chromosome 5.  “If two things that far apart turn out to be the same gene, then maybe a lot of other” forms of deafness will be too, Dr. King said.     Dr. King has also used genomic tools to help in the investigation of human rights abuses. In Argentina between 1975 and 1983 a period known as the Dirty War there were about 15,000–30,000 suspected political dissidents were “disappeared” by the ruling military junta. Many of their children disappeared as well other children were born to their imprisoned pregnant mothers. Instead of being returned to their families the children were taken into the households of members of the military and other junta sympathizers. The Abuelas de Plaza de Mayo was formed by the relatives of the disappeared to demand the return of the more than 400 children kidnapped by the military junta. To do so the grandmothers needed to identify who the children were. The Abuelas de Plaza de Mayo asked the American Association for the Advancement of Science to provide a geneticist who could help identify their missing grandchildren. In 1984, Dr. King began working with the Abuelas de Plaza de Mayo to provide evidence of kinship. Using human lymphocyte antigens and other genetic markers, Dr. King first calculated an “index of grand paternity” to determine the probability that a child was related to a grandparent. In December 1984, Paula Logares became the first child to be reunited with her biological family based on Dr. King’s genetic evidence.     Mary claire king has had many great discoveries in her lifetime. She’s found a gene to help with the further study of cancer, finding that were are closely related to chimpanzees or closer than we thought we were, and she helped with the human rights work. She is now 71 years of age and is still working to help make our world a better place. “I think there are two keys to being creatively productive. One is not being daunted by one’s fear of failure. The second is sheer perseverance.”Mary-Claire King

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